Interdisciplinary working groups of expert scientists review the published studies and evaluate the weight of the evidence that an agent can increase the risk of cancer. The principles, procedures, and scientific criteria that guide the evaluations are described in the Preamble to the IARC Monographs.
Since 1971, more than 900 agents have been evaluated, of which more than 400 have been identified as carcinogenic, probably carcinogenic, or possibly carcinogenic to humans.
Volume 107: Polychlorinated Biphenyls and Polybrominated Biphenyls
7 November 2014
We are pleased to announce that the Monograph on Polybrominated Biphenyls is now available on-line. The accompanying Monograph on Polychlorinated Biphenyls will be published subsequently.
Volume 111: Some Nanomaterials and Some Fibres
Launch of IARC Handbooks of Cancer Prevention website
28 August 2014
The IARC Monographs Programme is pleased to announce the launch of the IARC Handbooks of Cancer Prevention website. The IARC Handbooks of Cancer Prevention provide evaluations of various approaches to primary and secondary cancer prevention. Previous volumes have evaluated the cancer-preventive activity of chemopreventive agents, the effectiveness of screening, and the effectiveness of tobacco control. The new website provides a comprehensive overview of the IARC Handbooks series, with free access to PDFs of published volumes and lists of evaluations for all agents and activities evaluated so far, as well as updated Working Procedures and Guidelines for Observers for future volumes, and information about upcoming meetings. Visit the Handbooks website
25 June 2012 Volume 100 compiles information on tumour sites and mechanisms of carcinogenesis. About half of the agents classified in Group 1 were last reviewed more than 20 years ago, before mechanistic studies became prominent in evaluations of carcinogenicity. In addition, more recent epidemiological studies and animal cancer bioassays have demonstrated that many cancer hazards reported in earlier studies were later observed in other organs or through different exposure scenarios. Available at WHO Press