Interdisciplinary working groups of expert scientists review the published studies and evaluate the weight of the evidence that an agent can increase the risk of cancer. The principles, procedures, and scientific criteria that guide the evaluations are described in the Preamble to the IARC Monographs.
Since 1971, more than 900 agents have been evaluated, of which more than 400 have been identified as carcinogenic, probably carcinogenic, or possibly carcinogenic to humans.
For answers to commonly asked questions on the evaluation process, read the IARC Monographs Q&A.
Volume 112: Some Organophosphate Insecticides and Herbicides
29 July 2015
We are pleased to announce that the Monograph on Glyphosate is now available online. The remaining Monographs of Volume 112 will be published subsequently.
Volume 107: Polychlorinated Biphenyls and Polybrominated Biphenyls
30 June 2015
We are pleased to announce that this volume of the IARC Monographs is now available in its entirety online.
An article "Use of mechanistic data in the IARC evaluation of polychlorinated biphenyls" has also been published in Environmental Science and Pollution Research International.
25 June 2012 Volume 100 compiles information on tumour sites and mechanisms of carcinogenesis. About half of the agents classified in Group 1 were last reviewed more than 20 years ago, before mechanistic studies became prominent in evaluations of carcinogenicity. In addition, more recent epidemiological studies and animal cancer bioassays have demonstrated that many cancer hazards reported in earlier studies were later observed in other organs or through different exposure scenarios. Available at WHO Press