Interdisciplinary working groups of expert scientists review the published studies and evaluate the weight of the evidence that an agent can increase the risk of cancer. The principles, procedures, and scientific criteria that guide the evaluations are described in the Preamble to the IARC Monographs.
Since 1971, more than 900 agents have been evaluated, of which more than 400 have been identified as carcinogenic, probably carcinogenic, or possibly carcinogenic to humans.
For answers to commonly asked questions on the evaluation process, read the IARC Monographs Q&A.
Volume 110: Perfluorooctanoic Acid, Tetrafluoroethylene, Dichloromethane, 1,2-Dichloropropane, and 1,3-Propane Sultone
19 July 2016 We are pleased to announce that the Monograph on Perfluorooctanoic Acid (PFOA) is now available online. The remaining Monographs of Volume 110 will be published subsequently.
Volume 116: Coffee, Mate, and Very Hot Beverages
Volume 115: Some Industrial Chemicals
Volume 112: Some Organophosphate Insecticides and Herbicides
21 December 2015
We are pleased to announce that the Monographs on Diazinon and Malathion are now available online. The remaining Monographs of Volume 112 will be published subsequently.
Volume 109: Outdoor Air Pollution
17 December 2015
We are pleased to announce that the Monograph on Outdoor Air Pollution is now available online.
Key characteristics of carcinogens as a basis for organizing data on mechanisms of carcinogenesis
25 November 2015
We are pleased to announce the publication of Key characteristics of carcinogens as a basis for organizing data on mechanisms of carcinogenesis (Smith et al., 2015).
25 June 2012 Volume 100 compiles information on tumour sites and mechanisms of carcinogenesis. About half of the agents classified in Group 1 were last reviewed more than 20 years ago, before mechanistic studies became prominent in evaluations of carcinogenicity. In addition, more recent epidemiological studies and animal cancer bioassays have demonstrated that many cancer hazards reported in earlier studies were later observed in other organs or through different exposure scenarios. Available at WHO Press